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Ilginatinib [1239358-86-1]

Research Use Only
HY-19631A
MedChem Express
CAS Number1239358-86-1
Product group Chemicals
Estimated Purity95.07%
Molecular Weight389.43
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Ilginatinib [1239358-86-1]
  • Delivery Days Customer
    10
  • CAS Number
    1239358-86-1
  • Certification
    Research Use Only
  • Estimated Purity
    95.07%
  • Molecular Formula
    C21H20FN7
  • Molecular Weight
    389.43
  • Scientific Description
    Ilginatinib (NS-018) is a highly active and orally bioavailable JAK2 inhibitor, with an IC50 of 0.72 nM, 46-, 54-, and 31-fold selectivity for JAK2 over JAK1 (IC50, 33 nM), JAK3 (IC50, 39 nM), and Tyk2 (IC50, 22 nM).
  • SMILES
    CN1N=CC(C2=CC(N[C@H](C3=CC=C(F)C=C3)C)=NC(NC4=NC=CN=C4)=C2)=C1
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200