NSC 663284 [383907-43-5]
HY-100034
CAS Number383907-43-5
Product group Chemicals
Estimated Purity99.79%
Molecular Weight321.76
Overview
- SupplierMedChem Express
- Product NameNSC 663284 [383907-43-5]
- Delivery Days Customer10
- CAS Number383907-43-5
- Estimated Purity99.79%
- Molecular FormulaC15H16ClN3O3
- Molecular Weight321.76
- Scientific DescriptionNSC 663284 (DA-3003-1) is a potent, cell-permeable, and irreversible Cdc25 dual specificity phosphatase inhibitor, has an IC50 for Cdc25B2 of 0.21 microM. NSC 663284 exhibits mixed competitive kinetics against Cdc25A, Cdc25B(2), and Cdc25C with Ki values of 29, 95, and 89 nM, respectively. NSC 663284 inhibits NSD2 (IC50 of 170 nM) through a direct interaction with the catalytic SET domain (Kd of 370 nM).
- SMILESO=C(C(Cl)=C1NCCN2CCOCC2)C3=C(N=CC=C3)C1=O
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200