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NVP-ADW742 [475488-23-4]

Research Use Only
HY-10252
MedChem Express
CAS Number475488-23-4
Product group Chemicals
Estimated Purity98.98%
Molecular Weight453.58
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    NVP-ADW742 [475488-23-4]
  • Delivery Days Customer
    10
  • CAS Number
    475488-23-4
  • Certification
    Research Use Only
  • Estimated Purity
    98.98%
  • Molecular Formula
    C28H31N5O
  • Molecular Weight
    453.58
  • Scientific Description
    NVP-ADW742 (ADW742) is an orally active, selective IGF-1R tyrosine kinase inhibitor with an IC50 of 0.17 microM. NVP-ADW742 inhibits insulin receptor (InsR) with an IC50 of 2.8 microM. NVP-ADW742 induces pleiotropic antiproliferative/proapoptotic biologic sequelae in tumor cells.
  • SMILES
    NC1=C2C(N(C=C2C3=CC=CC(OCC4=CC=CC=C4)=C3)[C@H]5C[C@@H](C5)CN6CCCC6)=NC=N1
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200