NVP-BSK805 dihydrochloride [1942919-79-0]

MedChem Express

NVP-BSK805 dihydrochloride [1942919-79-0]

10

1942919-79-0

Research Use Only

98%

C27H30Cl2F2N6O

563.47

NVP-BSK805 dihydrochloride is an ATP-competitive JAK2 inhibitor, with IC50s of 0.48 nM, 31.63 nM, 18.68 nM, and 10.76 nM for JAK2 JH1 (JAK homology 1), JAK1 JH1, JAK3 JH1, and TYK2 JH1, respectively.

FC1=C(CN2CCOCC2)C(F)=CC(C3=C4N=C(C5=CN(C6CCNCC6)N=C5)C=NC4=CC=C3)=C1.Cl.Cl

2°C to 8°C,-20°C,-80°C

12352200