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NVP-TAE 226 [761437-28-9]

Research Use Only
HY-13203
MedChem Express
CAS Number761437-28-9
Product group Chemicals
Estimated Purity98.01%
Molecular Weight468.94
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    NVP-TAE 226 [761437-28-9]
  • Delivery Days Customer
    10
  • CAS Number
    761437-28-9
  • Certification
    Research Use Only
  • Estimated Purity
    98.01%
  • Molecular Formula
    C23H25ClN6O3
  • Molecular Weight
    468.94
  • Scientific Description
    NVP-TAE 226 (TAE226) is a potent and ATP-competitive dual FAK and IGF-1R inhibitor with IC50s of 5.5 nM and 140 nM, respectively. NVP-TAE 226 (TAE226) also effectively inhibits Pyk2 and insulin receptor (InsR) with IC50s of 3.5 nM and 44 nM, respectively.
  • SMILES
    O=C(C1=C(C=CC=C1)NC2=NC(NC3=C(C=C(C=C3)N4CCOCC4)OC)=NC=C2Cl)NC
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200