NXT629 [1454925-59-7]
HY-114263
CAS Number1454925-59-7
Product group Chemicals
Estimated Purity99.2%
Molecular Weight609.78
Overview
- SupplierMedChem Express
- Product NameNXT629 [1454925-59-7]
- Delivery Days Customer10
- CAS Number1454925-59-7
- Estimated Purity99.2%
- Molecular FormulaC35H39N5O3S
- Molecular Weight609.78
- Scientific DescriptionNXT629 is a potent, selective, and competitive PPAR-alpha antagonist, with an IC50 of 77 nM for human PPARalpha, shows high selectivity over other nuclear hormone receptor, such as PPARdelta, PPARgamma, ERbeta, GR and TRbeta, IC50s are 6.0, 15, 15.2, 32.5 and >100 microM, respectively. NXT629 has potent anti-tumor activity and inhibits experimental metastasis of cancer cell in animal models.
- SMILESO=S(C1=CC=CC=C1)(NC2=CC=C(C3=CC=C(CCCC(N4CC)=NN(CC5=CC=C(C(C)(C)C)C=C5)C4=O)C=C3)N=C2)=O
- Storage Instruction-20°C,-80°C
- UNSPSC12352200