Oglemilast [778576-62-8]

MedChem Express

Oglemilast [778576-62-8]

10

778576-62-8

98%

C20H13Cl2F2N3O5S

516.3

Oglemilast (GRC 3886) is a potent and orally active phosphodiesterase-4 (PDE4) inhibitor with an IC50 of 0.5 nM for PDE4D3. Oglemilast inhibits pulmonary cell infiltration, including eosinophilia and neutrophilia in vitro and in vivo. Oglemilast has the potential for inflammatory airway diseases.

O=C(C1=C2C(OC3=CC=C(NS(=O)(C)=O)C=C23)=C(OC(F)F)C=C1)NC4=C(Cl)C=NC=C4Cl

2°C to 8°C,-20°C,-80°C

12352200