Olaparib (AZD2281) [763113-22-0]
S1060
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameOlaparib (AZD2281) [763113-22-0]
- Delivery Days Customer9
- CertificationResearch Use Only
- Scientific DescriptionOlaparib (AZD2281, KU0059436) is a selective inhibitor of PARP1/2 with IC50 of 5 nM/1 nM in cell-free assays, 300-times less effective against tankyrase-1. Olaparib induces significant autophagy that is associated with mitophagy in cells with BRCA mutations.
- UNSPSC12352200