Tirabrutinib hydrochloride [1439901-97-9]
HY-15771A
Overview
- SupplierMedChem Express
- Product NameTirabrutinib hydrochloride [1439901-97-9]
- Delivery Days Customer10
- CAS Number1439901-97-9
- Estimated Purity98%
- Molecular FormulaC25H23ClN6O3
- Molecular Weight490.94
- Scientific DescriptionTirabrutinib (ONO-4059) hydrochloride is an orally active Brutons Tyrosine Kinase (BTK) inhibitor (can cross the blood-brain barrier (BBB)), with an IC50 of 6.8 nM. Tirabrutinib hydrochloride irreversibly and covalently binds to BTK and inhibits aberrant B cell receptor signaling. Tirabrutinib hydrochloride can be used in studies of autoimmune diseases and hematological malignancies.
- SMILESO=C1N(C2=CC=C(OC3=CC=CC=C3)C=C2)C4=C(N)N=CN=C4N1[C@H]5CN(C(C#CC)=O)CC5.[H]Cl
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200