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Tirabrutinib hydrochloride [1439901-97-9]

HY-15771A
MedChem Express
CAS Number1439901-97-9
Product group Chemicals
Estimated Purity98%
Molecular Weight490.94
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Tirabrutinib hydrochloride [1439901-97-9]
  • Delivery Days Customer
    10
  • CAS Number
    1439901-97-9
  • Estimated Purity
    98%
  • Molecular Formula
    C25H23ClN6O3
  • Molecular Weight
    490.94
  • Scientific Description
    Tirabrutinib (ONO-4059) hydrochloride is an orally active Brutons Tyrosine Kinase (BTK) inhibitor (can cross the blood-brain barrier (BBB)), with an IC50 of 6.8 nM. Tirabrutinib hydrochloride irreversibly and covalently binds to BTK and inhibits aberrant B cell receptor signaling. Tirabrutinib hydrochloride can be used in studies of autoimmune diseases and hematological malignancies.
  • SMILES
    O=C1N(C2=CC=C(OC3=CC=CC=C3)C=C2)C4=C(N)N=CN=C4N1[C@H]5CN(C(C#CC)=O)CC5.[H]Cl
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200