OSI-930 [728033-96-3]

MedChem Express

OSI-930 [728033-96-3]

10

728033-96-3

Research Use Only

98.13%

C22H16F3N3O2S

443.44

OSI-930 is an orally selective inhibitor of Kit, KDR and CSF-1R (c-Fms) with IC50s of 80 nM, 9 nM and 15 nM, respectively. OSI-930 also moderately inhibits Flt-1, c-Raf, Lck and low activity against PDGFRalpha/beta, Flt-3 and Abl. OSI-930 has antitumor activity.

O=C(C1=C(NCC2=CC=NC3=CC=CC=C23)C=CS1)NC4=CC=C(OC(F)(F)F)C=C4

2°C to 8°C,-20°C,-80°C

12352200