OTS964 [1338545-07-5]
S7648
Overview
- SupplierSelleck Chemicals
- Product NameOTS964 [1338545-07-5]
- Delivery Days Customer9
- CAS Number1338545-07-5
- CertificationResearch Use Only
- Scientific DescriptionOTS964 is a potent TOPK inhibitor with high affinity and selectivity and IC50 value is 28 nM. OTS964 is also a potent inhibitor of the cyclin-dependent kinase CDK11 with Kd of 40 nM. OTS964 treatment activates autophagy in glioma cells and induces apoptosis of human lung cancer cells in mouse xenografts.
- UNSPSC12352200