Palbociclib monohydrochloride [827022-32-2]

MedChem Express

Palbociclib monohydrochloride [827022-32-2]

10

827022-32-2

Research Use Only

95%

C24H30ClN7O2

483.99

Palbociclib (PD 0332991) monohydrochloride is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib monohydrochloride has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma.

O=C1C(C(C)=O)=C(C)C2=CN=C(NC3=NC=C(N4CCNCC4)C=C3)N=C2N1C5CCCC5.Cl

2°C to 8°C,-20°C,-80°C

12352200