Palbociclib isethionate [827022-33-3]

MedChem Express

Palbociclib isethionate [827022-33-3]

10

827022-33-3

Research Use Only

99.52%

C26H35N7O6S

573.66

Palbociclib (PD 0332991) isethionate is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib isethionate has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma.

CC(C1=C(N2C3CCCC3)N=C(NC4=NC=C(N5CCNCC5)C=C4)N=C1)=C(C(C)=O)C2=O.OCCS(O)(=O)=O

2°C to 8°C,-20°C,-80°C

12352200