Paritaprevir [1216941-48-8]
HY-12594
Overview
- SupplierMedChem Express
- Product NameParitaprevir [1216941-48-8]
- Delivery Days Customer10
- CAS Number1216941-48-8
- CertificationResearch Use Only
- Estimated Purity98%
- Molecular FormulaC40H43N7O7S
- Molecular Weight765.88
- Scientific DescriptionParitaprevir (ABT-450) is a potent, orally active and antiviral non-structural protein 3/4A (NS3/4A) protease inhibitor with EC50s of 1 and 0.21 nM against HCV 1a and 1b, respectively. Paritaprevir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.31 microM. Paritaprevir is metabolized primarily by cytochrome P450 (CYP) 3A. The plasma concentration and half-life of Paritaprevir can be enhanced by Ritonavir (a CYP450 inhibitor).
- SMILESO=C([C@]1(NC([C@@]2([H])N3C[C@H](OC4=C(C=CC=C5)C5=C6C(C=CC=C6)=N4)C2)=O)[C@H](/C=C\CCCCC[C@H](NC(C7=NC=C(C)N=C7)=O)C3=O)C1)NS(=O)(C8CC8)=O
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200