Lenumlostat [2007885-39-2]

MedChem Express

Lenumlostat [2007885-39-2]

10

2007885-39-2

95.11%

C18H17F4N3O3

399.34

PAT-1251 is a potent, selective and oral lysyl oxidase-like 2 (LOXL2) inhibitor, with IC50s of 0.71 and 1.17 microM for hLOXL2 and hLOXL3, respectively, and also potently inhibits mouse, rat, and dog LOXL2 (IC50s, 0.10, 0.12, and 0.16 microM, respectively); PAT-1251 is used in the research of fibrotic diseases.

O=C(C1=CC=CC(OC2=NC(C(F)(F)F)=CC(CN)=C2)=C1)N3C[C@@H](F)[C@H](O)C3

2°C to 8°C,-20°C,-80°C

12352200