Pazopanib [444731-52-6]

MedChem Express

Pazopanib [444731-52-6]

10

444731-52-6

Research Use Only

95%

C21H23N7O2S

437.52

Pazopanib (GW786034) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRbeta, c-Kit, FGFR1, and c-Fms with IC50s of 10, 30, 47, 84, 74, 140 and 146 nM, respectively.

O=S(C1=CC(NC2=NC=CC(N(C3=CC4=NN(C(C)=C4C=C3)C)C)=N2)=CC=C1C)(N)=O

2°C to 8°C,-20°C,-80°C

12352200