PCI 29732 [330786-25-9]
HY-18010
CAS Number330786-25-9
Product group Chemicals
Estimated Purity99.86%
Molecular Weight371.44
Overview
- SupplierMedChem Express
- Product NamePCI 29732 [330786-25-9]
- Delivery Days Customer10
- CAS Number330786-25-9
- CertificationResearch Use Only
- Estimated Purity99.86%
- Molecular FormulaC22H21N5O
- Molecular Weight371.44
- Scientific DescriptionPCI 29732 is a potent, orally active, reversible BTK inhibitor with Kiapp values of 8.2, 4.6, and 2.5 nM for BTK, Lck and Lyn, respectively. PCI 29732 shows only modest inhibitory activity against Itk, another Tec family kinase. PCI 29732 inhibits the function of ABCG2 by competitively binding to the ATP-binding site of ABCG2.
- SMILESNC1=NC=NC2=C1C(C3=CC=C(OC4=CC=CC=C4)C=C3)=NN2C5CCCC5
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200