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Mirdametinib [391210-10-9]

Research Use Only
HY-10254
MedChem Express
CAS Number391210-10-9
Product group Chemicals
Estimated Purity98.8%
Molecular Weight482.19
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Mirdametinib [391210-10-9]
  • Delivery Days Customer
    10
  • CAS Number
    391210-10-9
  • Certification
    Research Use Only
  • Estimated Purity
    98.8%
  • Molecular Formula
    C16H14F3IN2O4
  • Molecular Weight
    482.19
  • Scientific Description
    Mirdametinib (PD0325901) is an orally active, selective and non-ATP-competitive MEK inhibitor with an IC50 of 0.33 nM. Mirdametinib exhibits a Kiapp of 1 nM against activated MEK1 and MEK2. Mirdametinib suppresses the expression of p-ERK1/2 and induces apoptosis. Mirdametinib has anti-cancer activity for a broad spectrum of human tumor xenografts.
  • SMILES
    O=C(C1=CC=C(C(F)=C1NC2=CC=C(I)C=C2F)F)NOC[C@H](O)CO
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200