PD168393 [194423-15-9]

MedChem Express

PD168393 [194423-15-9]

10

194423-15-9

98.6%

C17H13BrN4O

369.22

PD168393 is a potent, selective and cell-permeable inhibitor of EGFR tyrosine kinase and ErbB2. PD168393 irreversiblely inactivates EGF receptor ( IC50=0.7 nM) and is inactive against insulin receptor, PDGFR, FGFR and PKC.

C=CC(NC1=CC2=C(NC3=CC=CC(Br)=C3)N=CN=C2C=C1)=O

2°C to 8°C,-20°C,-80°C

12352200