Pexmetinib [945614-12-0]

MedChem Express

Pexmetinib [945614-12-0]

10

945614-12-0

98.3%

C31H33FN6O3

556.63

Pexmetinib is a potent Tie-2 and p38 MAPK dual inhibitor, with IC50s of 1 nM, 35 nM and 26 nM for Tie-2, p38alpha and p38beta, respectively, and can be used in the research of acute myeloid leukemia.

O=C(NCC1=CC(F)=CC=C1OC2=CC3=C(N(CCO)N=C3)C=C2)NC4=CC(C(C)(C)C)=NN4C5=CC=C(C)C=C5

-20°C,-80°C

12352200