PF-04691502 [1013101-36-4]

Selleck Chemicals

PF-04691502 [1013101-36-4]

9

1013101-36-4

Research Use Only

PF-04691502 (PF4691502) is an ATP-competitive PI3K(alfa/bèta/delta/gamma)/mTOR dual inhibitor with Ki of 1.8 nM/2.1 nM/1.6 nM/1.9 nM and 16 nM in cell-free assays, little activity against either Vps34, AKT, PDK1, p70S6K, MEK, ERK, p38, or JNK. PF-04691502 induces apoptosis. Phase 2.

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