PF-5274857 [1373615-35-0]
HY-13459
CAS Number1373615-35-0
Product group Chemicals
Estimated Purity98.89%
Molecular Weight436.96
Overview
- SupplierMedChem Express
- Product NamePF-5274857 [1373615-35-0]
- Delivery Days Customer10
- CAS Number1373615-35-0
- Estimated Purity98.89%
- Molecular FormulaC20H25ClN4O3S
- Molecular Weight436.96
- Scientific DescriptionPF-5274857 is a potent, selective, orally active and brain-penetrant antagonist of Smo, with an IC50 of 5.8 nM and Ki of 4.6 nM. PF-5274857 has potential for research of tumor types including brain tumors and brain metastasis driven by an activated Hh pathway.
- SMILESO=C(N1CCN(C2=NC=C(Cl)C(C3=NC=C(C)C=C3C)=C2)CC1)CCS(=O)(C)=O
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200