PFK-158 [1462249-75-7]
HY-12203
CAS Number1462249-75-7
Product group Chemicals
Estimated Purity98.52%
Molecular Weight328.29
Overview
- SupplierMedChem Express
- Product NamePFK-158 [1462249-75-7]
- Delivery Days Customer10
- CAS Number1462249-75-7
- CertificationResearch Use Only
- Estimated Purity98.52%
- Molecular FormulaC18H11F3N2O
- Molecular Weight328.29
- Scientific DescriptionPFK-158 is a potent and selective PFKFB3 inhibitor with an IC50 value 137 nM. PFK-158 reduces glucose uptake, ATP production, lactate release, and induces apoptosis and autophagy in cancer cells. PFK-158 has broad anti-tumor activity. PFK-158 can also enhance Colistins resistance to bacteria.
- SMILESO=C(C1=CC=NC=C1)/C=C/C2=NC3=CC(C(F)(F)F)=CC=C3C=C2
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200