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PI-1840 [1401223-22-0]

Research Use Only
HY-12286
MedChem Express
CAS Number1401223-22-0
Product group Chemicals
Estimated Purity99.11%
Molecular Weight394.47
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    PI-1840 [1401223-22-0]
  • Delivery Days Customer
    6
  • CAS Number
    1401223-22-0
  • Certification
    Research Use Only
  • Estimated Purity
    99.11%
  • Molecular Formula
    C22H26N4O3
  • Molecular Weight
    394.47
  • Scientific Description
    PI-1840 is a potent and selective chymotrypsin-like (CT-L) inhibitor for with an IC50 value of 27 nM. PI-1840 inhibits cell proliferation and arrest cell cycle at G2/M phase. PI-1840 induces apoptosis and induces autophagy. PI-1840 induces the accumulation of proteasome substrates p27, Bax, and IkappaB-alpha.
  • SMILES
    O=C(N(C(C)C)CC1=NC(C2=CC=CN=C2)=NO1)COC3=CC=C(CCC)C=C3
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200