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Pico145 [1628287-16-0]

HY-101507
MedChem Express
CAS Number1628287-16-0
Product group Chemicals
Estimated Purity99.4%
Molecular Weight524.88
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Pico145 [1628287-16-0]
  • Delivery Days Customer
    10
  • CAS Number
    1628287-16-0
  • Estimated Purity
    99.4%
  • Molecular Formula
    C23H20ClF3N4O5
  • Molecular Weight
    524.88
  • Scientific Description
    Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels, inhibits (-)-englerin A-activated TRPC4/TRPC5 channels, with IC50s of 0.349 and 1.3 nM in cells, and shows no effect on TRPC3, TRPC6, TRPV1, TRPV4, TRPA1, TRPM2, TRPM8.
  • SMILES
    O=C1C2=C(N=C(OC3=CC=CC(OC(F)(F)F)=C3)N2CC4=CC=C(Cl)C=C4)N(C)C(N1CCCO)=O
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200