PIK-75 hydrochloride [372196-77-5]
HY-13281
Overview
- SupplierMedChem Express
- Product NamePIK-75 hydrochloride [372196-77-5]
- Delivery Days Customer10
- CAS Number372196-77-5
- CertificationResearch Use Only
- Estimated Purity98%
- Molecular FormulaC16H15BrClN5O4S
- Molecular Weight488.74
- Scientific DescriptionPIK-75 hydrochloride is a reversible DNA-PK and p110alpha-selective inhibitor, which inhibits DNA-PK, p110alpha and p110gamma with IC50s of 2, 5.8 and 76 nM, respectively. PIK-75 hydrochloride inhibits p110alpha >200-fold more potently than p110beta (IC50=1.3 microM). PIK-75 hydrochloride induces apoptosis.
- SMILESBrC(C=C1)=CN2C1=NC=C2/C=N/N(S(=O)(C3=C(C=CC([N+]([O-])=O)=C3)C)=O)C.[H]Cl
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200