PIM-447 dihydrochloride [1820565-69-2]
HY-19322B
CAS Number1820565-69-2
Product group Chemicals
Estimated Purity98.25%
Molecular Weight513.38
Overview
- SupplierMedChem Express
- Product NamePIM-447 dihydrochloride [1820565-69-2]
- Delivery Days Customer10
- CAS Number1820565-69-2
- Estimated Purity98.25%
- Molecular FormulaC24H25Cl2F3N4O
- Molecular Weight513.38
- Scientific DescriptionPIM447 dihydrochloride (LGH447 dihydrochloride) is a potent, orally available, and selective pan-PIM kinase inhibitor, with Ki values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively. PIM447 dihydrochloride displays dual antimyeloma and bone-protective effects. PIM447 dihydrochloride induces apoptosis.
- SMILESO=C(C1=NC(C2=C(F)C=CC=C2F)=C(F)C=C1)NC3=C([C@H]4C[C@@H](N)C[C@@H](C)C4)C=CN=C3.Cl.Cl
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200