PPQ-102 [931706-15-9]

MedChem Express

PPQ-102 [931706-15-9]

10

931706-15-9

Research Use Only

99.82%

C26H22N4O3

438.48

PPQ-102 (CFTR Inhibitor) is a reversible CFTR inhibitor that completely inhibits CFTR chloride currents (IC50 ~90 nM). PPQ-102 is not affected by membrane potential-dependent cell allocation or blocking efficiency (uncharged at physiological pH) and effectively prevents cyst enlargement in polycystic kidney disease.

CN1C(C2=C(C3=CC=CC=C3)N4C5=CC=CC=C5NC(C6=CC=C(C)O6)C4=C2N(C)C1=O)=O

2°C to 8°C,-20°C,-80°C

12352200