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ProductsBack/Prucalopride [179474-81-8]

Prucalopride [179474-81-8]

Research Use Only
HY-14151
MedChem Express
CAS Number179474-81-8
DownloadMSDS
Product group Chemicals
Estimated Purity99.83%
Molecular Weight367.87
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Prucalopride [179474-81-8]
  • Delivery Days Customer
    10
  • CAS Number
    179474-81-8
  • Certification
    Research Use Only
  • Estimated Purity
    99.83%
  • Molecular Formula
    C18H26ClN3O3
  • Molecular Weight
    367.87
  • Scientific Description
    Prucalopride is an orally active, selective and specific 5-HT 4 receptor agonist (high affinity), with pKis of 8.6 and 8.1 for human 5-HT4a/4b receptors, respectively. Prucalopride improves intestinal motility by promoting regeneration of the intestinal nervous system in rats. Prucalopride also shows anticancer activity by blocking of the PI3K/AKT/mTor signaling pathway. Prucalopride can be used in studies of chronic constipation, pseudo-intestinal obstruction and cancer.
  • SMILES
    ClC1=C(N)C(CCO2)=C2C(C(NC3CCN(CCCOC)CC3)=O)=C1
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200