Bio-Connect

Pyridone 6 [457081-03-7]

Research Use Only
HY-14435
MedChem Express
CAS Number457081-03-7
Product group Chemicals
Estimated Purity98.84%
Molecular Weight309.34
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    MedChem Express
  • Product Name
    Pyridone 6 [457081-03-7]
  • Delivery Days Customer
    10
  • CAS Number
    457081-03-7
  • Certification
    Research Use Only
  • Estimated Purity
    98.84%
  • Molecular Formula
    C18H16FN3O
  • Molecular Weight
    309.34
  • Scientific Description
    Pyridone 6 is a pan-JAK inhibitor, which potently inhibits the JAK kinase family, with IC50s of 1 nM for JAK2 and TYK2, 5 nM for JAK3, and 15 nM for JAK1, while displaying significantly weaker affinities (130 nM to >10 mM) for other protein tyrosine kinases.
  • SMILES
    FC1=CC2=C(C(NC=C3)=O)C3=C(N=C(C(C)(C)C)N4)C4=C2C=C1
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200