Pyridone 6 [457081-03-7]
HY-14435
CAS Number457081-03-7
Product group Chemicals
Estimated Purity98.84%
Molecular Weight309.34
Overview
- SupplierMedChem Express
- Product NamePyridone 6 [457081-03-7]
- Delivery Days Customer10
- CAS Number457081-03-7
- CertificationResearch Use Only
- Estimated Purity98.84%
- Molecular FormulaC18H16FN3O
- Molecular Weight309.34
- Scientific DescriptionPyridone 6 is a pan-JAK inhibitor, which potently inhibits the JAK kinase family, with IC50s of 1 nM for JAK2 and TYK2, 5 nM for JAK3, and 15 nM for JAK1, while displaying significantly weaker affinities (130 nM to >10 mM) for other protein tyrosine kinases.
- SMILESFC1=CC2=C(C(NC=C3)=O)C3=C(N=C(C(C)(C)C)N4)C4=C2C=C1
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200