Pyrimethamine [58-14-0]

MedChem Express

Pyrimethamine [58-14-0]

10

58-14-0

Research Use Only

99.83%

C12H13ClN4

248.71

Pyrimethamine (Pirimecidan) is a potent, orally active dihydrofolate reductase (DHFR) inhibitor. Pyrimethamine is an antimalarial agent. Pyrimethamine affects the nucleoprotein metabolism of malarial parasites by interference in the folic-folinic acid systems and affects cell division by inhibiting the conversion of dihydrofolate to tetrahydrofolate.

NC1=NC(N)=C(C2=CC=C(Cl)C=C2)C(CC)=N1

2°C to 8°C,-20°C,-80°C

12352200