Pyrotinib dimaleate [1397922-61-0]

MedChem Express

Pyrotinib dimaleate [1397922-61-0]

10

1397922-61-0

99.63%

C40H39ClN6O11

815.22

Pyrotinib dimaleate (SHR-1258 dimaleate) is a potent and selective EGFR/HER2 dual inhibitor with IC50s of 13 and 38 nM, respectively.

O=C(NC1=C(OCC)C=C2N=CC(C#N)=C(NC3=CC=C(OCC4=NC=CC=C4)C(Cl)=C3)C2=C1)/C=C/[C@@H]5N(C)CCC5.O=C(O)/C=C\C(O)=O.O=C(O)/C=C\C(O)=O

2°C to 8°C,-20°C,-80°C

12352200