PYZD-4409 [423148-78-1]

MedChem Express

PYZD-4409 [423148-78-1]

10

423148-78-1

Research Use Only

98%

C14H7ClFN3O5

351.67

PYZD-4409 is a specific inhibitor of the ubiquitin-activating enzyme UBA1 with an IC50 of 20 microM (cell-free enzymatic assay). PYZD-4409 induces cell death in malignant cells and preferentially inhibits the clonogenic growth of primary acute myeloid leukemia cells.

FC1=CC=C(N2C(/C(C(N2)=O)=C\C3=CC=C([N+]([O-])=O)O3)=O)C=C1Cl

2°C to 8°C,-20°C,-80°C

12352200