QS11 [944328-88-5]

MedChem Express

QS11 [944328-88-5]

10

944328-88-5

Research Use Only

99.22%

C36H33N5O2

567.68

QS11 is an inhibitor of ARFGAP1 (ADP-ribosylation factor GTPase-activating protein 1), with an EC50 of 1.5 microM. QS11 modulates Wnt/beta-catenin signaling through an effect on protein trafficking. QS11 inhibits migration of ARFGAP overexpressing breast cancer cells.

OC[C@H](CC1=CC=CC=C1)NC2=C3C(N(CC4=CC=C(C5=CC=CC=C5)C=C4)C=N3)=NC(OC6=CC=C(CCC7)C7=C6)=N2

2°C to 8°C,-20°C,-80°C

12352200