Bio-Connect

R112 [575474-82-7]

Research Use Only
HY-16420
MedChem Express
CAS Number575474-82-7
Product group Chemicals
Estimated Purity99.23%
Molecular Weight312.3
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    R112 [575474-82-7]
  • Delivery Days Customer
    10
  • CAS Number
    575474-82-7
  • Certification
    Research Use Only
  • Estimated Purity
    99.23%
  • Molecular Formula
    C16H13FN4O2
  • Molecular Weight
    312.3
  • Scientific Description
    R112 is a fast and reversible inhibitor of spleen tyrosine kinase (Syk) kinase. R112 inhibits Syk kinase activity with an IC50 value of 226 nM and a Ki value of 96 nM. R112 inhibits IgE-FcepsilonRI signaling pathway. R112 can be used for the research of allergic rhinitis.
  • SMILES
    FC1=CN=C(NC2=CC(O)=CC=C2)N=C1NC3=CC(O)=CC=C3
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200