R121919 [195055-03-9]

MedChem Express

R121919 [195055-03-9]

10

195055-03-9

99.45%

C22H32N6

380.53

R121919 (NBI30775) is a potent small-molecule CRF1 receptor antagonist with a Ki of 2 to 5 nM for the CRF1 receptor and over 1000-fold weaker activity at the CRF2 receptor, CRF-binding protein, or 70 other receptor types.

CCCN(C1=CC(C)=NC2=C(C3=CN=C(N(C)C)C=C3C)C(C)=NN21)CCC

2°C to 8°C,-20°C,-80°C

12352200