Fostamatinib [901119-35-5]

MedChem Express

Fostamatinib [901119-35-5]

10

901119-35-5

98.61%

C23H26FN6O9P

580.46

Fostamatinib (R788) is the oral proagent of the active compound R406. R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM. R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM).

COC1=CC(NC2=NC=C(C(NC3=NC(N4COP(O)(O)=O)=C(C=C3)OC(C)(C)C4=O)=N2)F)=CC(OC)=C1OC

2°C to 8°C,-20°C,-80°C

12352200