Ranirestat [147254-64-6]
HY-15314
Overview
- SupplierMedChem Express
- Product NameRanirestat [147254-64-6]
- Delivery Days Customer10
- CAS Number147254-64-6
- CertificationResearch Use Only
- Estimated Purity96.1%
- Molecular FormulaC17H11BrFN3O4
- Molecular Weight420.19
- Scientific DescriptionRanirestat (AS-3201) potent and orally active aldose reductase (AR) inhibitor with IC50s of 11 nM and 15 nM for rat lens AR and recombinant human AR, respectively, and a Ki of 0.38 nM for recombinant human AR. Ranirestat has the potential for diabetic sensorimotor polyneuropathy treatment. Ranirestat also has a neuroprotective effect on diabetic retinas.
- SMILESO=C(N1CC2=CC=C(Br)C=C2F)C3=CC=CN3[C@]4(C(NC(C4)=O)=O)C1=O
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200