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Ranirestat [147254-64-6]

Research Use Only
HY-15314
MedChem Express
CAS Number147254-64-6
Product group Chemicals
Estimated Purity96.1%
Molecular Weight420.19
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Ranirestat [147254-64-6]
  • Delivery Days Customer
    10
  • CAS Number
    147254-64-6
  • Certification
    Research Use Only
  • Estimated Purity
    96.1%
  • Molecular Formula
    C17H11BrFN3O4
  • Molecular Weight
    420.19
  • Scientific Description
    Ranirestat (AS-3201) potent and orally active aldose reductase (AR) inhibitor with IC50s of 11 nM and 15 nM for rat lens AR and recombinant human AR, respectively, and a Ki of 0.38 nM for recombinant human AR. Ranirestat has the potential for diabetic sensorimotor polyneuropathy treatment. Ranirestat also has a neuroprotective effect on diabetic retinas.
  • SMILES
    O=C(N1CC2=CC=C(Br)C=C2F)C3=CC=CN3[C@]4(C(NC(C4)=O)=O)C1=O
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200