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Rapamycin [53123-88-9]

HY-10219
MedChem Express
CAS Number53123-88-9
Product group Chemicals
Estimated Purity96.35%
Molecular Weight914.17
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Rapamycin [53123-88-9]
  • Delivery Days Customer
    10
  • CAS Number
    53123-88-9
  • Estimated Purity
    96.35%
  • Molecular Formula
    C51H79NO13
  • Molecular Weight
    914.17
  • Scientific Description
    Rapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant.
  • SMILES
    O=C([C@@]1(O)[C@@H](CC[C@@H](C[C@@H](/C(C)=C/C=C/C=C/[C@H](C[C@@H](C)C([C@@H]([C@@H](/C(C)=C/[C@H]2C)O)OC)=O)C)OC)O1)C)C(N3CCCC[C@H]3C(O[C@@H](CC2=O)[C@@H](C[C@H]4C[C@H]([C@H](O)CC4)OC)C)=O)=O
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200