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Regorafenib [755037-03-7]

Research Use Only
HY-10331
MedChem Express
CAS Number755037-03-7
Product group Chemicals
Estimated Purity98.99%
Molecular Weight482.82
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Regorafenib [755037-03-7]
  • Delivery Days Customer
    10
  • CAS Number
    755037-03-7
  • Certification
    Research Use Only
  • Estimated Purity
    98.99%
  • Molecular Formula
    C21H15ClF4N4O3
  • Molecular Weight
    482.82
  • Scientific Description
    Regorafenib (BAY 73-4506) is an orally active and potent multi-targeted receptor tyrosine kinase inhibitor, with IC50 values of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3, PDGFRbeta, Kit, RET and Raf-1, respectively. Regorafenib shows very robust antitumor and antiangiogenic activity.
  • SMILES
    O=C(NC1=CC=C(C(C(F)(F)F)=C1)Cl)NC2=CC=C(OC3=CC(C(NC)=O)=NC=C3)C=C2F
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200