MC180295 [2237942-08-2]

MedChem Express

MC180295 [2237942-08-2]

10

2237942-08-2

Research Use Only

98.41%

C17H18N4O3S

358.41

MC180295 ((rel)-MC180295) is a potent and selective CDK9-Cyclin T1 inhibitor, with an IC50 of 5 nM, at least 22-fold more selective for CDK9 over other CDKs. MC180295 also inhibits GSK-3alpha and GSK-3beta. MC180295 ((rel)-MC180295) has potent anti-tumor effect.

NC1=C(C(C2=CC=CC=C2[N+]([O-])=O)=O)SC(N[C@@H]3[C@H](C4)CC[C@H]4C3)=N1

2°C to 8°C,-20°C,-80°C

12352200