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RGB-286638 [784210-87-3]

HY-15504
MedChem Express
CAS Number784210-87-3
Product group Chemicals
Estimated Purity98.44%
Molecular Weight618.55
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Overview

  • Supplier
    MedChem Express
  • Product Name
    RGB-286638 [784210-87-3]
  • Delivery Days Customer
    10
  • CAS Number
    784210-87-3
  • Estimated Purity
    98.44%
  • Molecular Formula
    C29H37Cl2N7O4
  • Molecular Weight
    618.55
  • Scientific Description
    RGB-286638 is a CDK inhibitor that inhibits the kinase activity of cyclin T1-CDK9, cyclin B1-CDK1, cyclin E-CDK2, cyclin D1-CDK4, cyclin E-CDK3, and p35-CDK5 with IC50s of 1, 2, 3, 4, 5 and 5 nM, respectively; also inhibits GSK-3beta, TAK1, Jak2 and MEK1, with IC50s of 3, 5, 50, and 54 nM.
  • SMILES
    O=C(NN1CCOCC1)NC2=CC=CC(C3=C4C(C5=CC=C(CN6CCN(CCOC)CC6)C=C5)=NN3)=C2C4=O.[H]Cl.[H]Cl
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200