Rhosin hydrochloride [1281870-42-5]
HY-12646
CAS Number1281870-42-5
Product group Chemicals
Estimated Purity99.67%
Molecular Weight394.86
Overview
- SupplierMedChem Express
- Product NameRhosin hydrochloride [1281870-42-5]
- Delivery Days Customer10
- CAS Number1281870-42-5
- CertificationResearch Use Only
- Estimated Purity99.67%
- Molecular FormulaC20H19ClN6O
- Molecular Weight394.86
- Scientific DescriptionRhosin hydrochloride is a potent, specific RhoA subfamily Rho GTPases inhibitor. Rhosin hydrochloride specifically binds to RhoA to inhibit RhoA-GEF interaction with a Kd of ~ 0.4 uM, and does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin hydrochloride induces cell apoptosis. Rhosin hydrochloride promotes stress resiliency through enhancing D1-MSN plasticity and reducing hyperexcitability.
- SMILESO=C(N/N=C/C1=CC=C2N=CC=NC2=C1)[C@H](N)CC3=CNC4=C3C=CC=C4.[H]Cl
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200