Rigosertib [592542-59-1]
HY-12037A
CAS Number592542-59-1
Product group Chemicals
Estimated Purity96.02%
Molecular Weight451.49
Overview
- SupplierMedChem Express
- Product NameRigosertib [592542-59-1]
- Delivery Days Customer10
- CAS Number592542-59-1
- Estimated Purity96.02%
- Molecular FormulaC21H25NO8S
- Molecular Weight451.49
- Scientific DescriptionRigosertib (ON-01910) is a multi-kinase inhibitor and a selective anti-cancer agent, which induces apoptosis by inhibition the PI3 kinase/Akt pathway, promots the phosphorylation of histone H2AX and induces G2/M arrest in cell cycle. Rigosertib is a selective and non-ATP-competitive inhibitor of PLK1 with an IC50 of 9 nM.
- SMILESCOC1=CC=C(C=C1NCC(O)=O)CS(/C=C/C2=C(C=C(C=C2OC)OC)OC)(=O)=O.[(E)]
- Storage Instruction-20°C
- UNSPSC12352200