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Rigosertib sodium [592542-60-4]

Research Use Only
HY-12037
MedChem Express
CAS Number592542-60-4
Product group Chemicals
Estimated Purity95.91%
Molecular Weight473.47
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Rigosertib sodium [592542-60-4]
  • Delivery Days Customer
    10
  • CAS Number
    592542-60-4
  • Certification
    Research Use Only
  • Estimated Purity
    95.91%
  • Molecular Formula
    C21H24NNaO8S
  • Molecular Weight
    473.47
  • Scientific Description
    Rigosertib sodium (ON-01910 sodium) is a multi-kinase inhibitor and a selective anti-cancer agent, which induces apoptosis by inhibition the PI3K/Akt pathway, promotes the phosphorylation of histone H2AX and induces G2/M arrest in cell cycle. Rigosertib sodium is a selective and non-ATP-competitive inhibitor of PLK1 with an IC50 of 9 nM.
  • SMILES
    COC1=CC=C(C=C1NCC(O[Na])=O)CS(/C=C/C2=C(C=C(C=C2OC)OC)OC)(=O)=O
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200