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RN-1734 [946387-07-1]

Research Use Only
HY-19975
MedChem Express
CAS Number946387-07-1
Product group Chemicals
Estimated Purity99.01%
Molecular Weight353.31
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    RN-1734 [946387-07-1]
  • Delivery Days Customer
    10
  • CAS Number
    946387-07-1
  • Certification
    Research Use Only
  • Estimated Purity
    99.01%
  • Molecular Formula
    C14H22Cl2N2O2S
  • Molecular Weight
    353.31
  • Scientific Description
    RN-1734 is selective antagonist of the TRPV4 channel, completely antagonizes 4alphaPDD-mediated activation of TRPV4 with comparable, low micromolar IC50s for all three species (hTRPV4: 2.3 microM, mTRPV4: 5.9 microM, rTRPV4: 3.2 microM). RN-1734 clearly decreases the production of tumor necrosis factor alpha (TNF-alpha) and interleukin 1beta (IL-1beta) without altering the number of olig2-positive cells.
  • SMILES
    O=S(C1=CC=C(Cl)C=C1Cl)(N(C(C)C)CCNC(C)C)=O
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200