RN-1734 [946387-07-1]
HY-19975
CAS Number946387-07-1
Product group Chemicals
Estimated Purity99.01%
Molecular Weight353.31
Overview
- SupplierMedChem Express
- Product NameRN-1734 [946387-07-1]
- Delivery Days Customer10
- CAS Number946387-07-1
- CertificationResearch Use Only
- Estimated Purity99.01%
- Molecular FormulaC14H22Cl2N2O2S
- Molecular Weight353.31
- Scientific DescriptionRN-1734 is selective antagonist of the TRPV4 channel, completely antagonizes 4alphaPDD-mediated activation of TRPV4 with comparable, low micromolar IC50s for all three species (hTRPV4: 2.3 microM, mTRPV4: 5.9 microM, rTRPV4: 3.2 microM). RN-1734 clearly decreases the production of tumor necrosis factor alpha (TNF-alpha) and interleukin 1beta (IL-1beta) without altering the number of olig2-positive cells.
- SMILESO=S(C1=CC=C(Cl)C=C1Cl)(N(C(C)C)CCNC(C)C)=O
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200