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RN486 [1242156-23-5]

Research Use Only
HY-18018
MedChem Express
CAS Number1242156-23-5
Product group Chemicals
Estimated Purity99.13%
Molecular Weight606.69
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    RN486 [1242156-23-5]
  • Delivery Days Customer
    10
  • CAS Number
    1242156-23-5
  • Certification
    Research Use Only
  • Estimated Purity
    99.13%
  • Molecular Formula
    C35H35FN6O3
  • Molecular Weight
    606.69
  • Scientific Description
    RN486 is a potent, selective and orally active Btk inhibitor with an IC50 of 4.0 nM and a Kd of 0.31 nM. RN486 is less active for other kinases. RN486 can be used for rheumatoid arthritis and systemic lupus erythematosus research.
  • SMILES
    O=C1C(NC2=CC=C(N3CCN(C)CC3)C=N2)=CC(C4=CC=CC(N5C=CC(C=C(C6CC6)C=C7F)=C7C5=O)=C4CO)=CN1C
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200