Roflumilast [162401-32-3]

MedChem Express

Roflumilast [162401-32-3]

10

162401-32-3

Research Use Only

98%

C17H14Cl2F2N2O3

403.21

Roflumilast (APTA-2217) is a selective PDE4 inhibitor with IC50s of 0.7, 0.9, 0.7, and 0.2 nM for PDE4A1, PDEA4, PDEB1, and PDEB2, respectively, without affecting PDE1, PDE2, PDE3 or PDE5 isoenzymes from various cells.

O=C(NC1=C(Cl)C=NC=C1Cl)C2=CC=C(OC(F)F)C(OCC3CC3)=C2

2°C to 8°C,-20°C,-80°C

12352200