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Rosuvastatin Calcium [147098-20-2]

Research Use Only
HY-17504
MedChem Express
CAS Number147098-20-2
Product group Chemicals
Estimated Purity96.75%
Molecular Weight500.57
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Rosuvastatin Calcium [147098-20-2]
  • Delivery Days Customer
    10
  • CAS Number
    147098-20-2
  • Certification
    Research Use Only
  • Estimated Purity
    96.75%
  • Molecular Formula
    C22H27Ca0.5FN3O6S
  • Molecular Weight
    500.57
  • Scientific Description
    Rosuvastatin Calcium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Calcium potently blocks hERG current with an IC50 of 195 nM. Rosuvastatin Calcium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Calcium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.
  • SMILES
    O=C([O-])C[C@H](O)C[C@H](O)/C=C/C1=C(C(C)C)N=C(N(C)S(=O)(C)=O)N=C1C2=CC=C(F)C=C2.[0.5Ca2+]
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200