Rosuvastatin Calcium [147098-20-2]
HY-17504
CAS Number147098-20-2
Product group Chemicals
Estimated Purity96.75%
Molecular Weight500.57
Overview
- SupplierMedChem Express
- Product NameRosuvastatin Calcium [147098-20-2]
- Delivery Days Customer10
- CAS Number147098-20-2
- CertificationResearch Use Only
- Estimated Purity96.75%
- Molecular FormulaC22H27Ca0.5FN3O6S
- Molecular Weight500.57
- Scientific DescriptionRosuvastatin Calcium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Calcium potently blocks hERG current with an IC50 of 195 nM. Rosuvastatin Calcium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Calcium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.
- SMILESO=C([O-])C[C@H](O)C[C@H](O)/C=C/C1=C(C(C)C)N=C(N(C)S(=O)(C)=O)N=C1C2=CC=C(F)C=C2.[0.5Ca2+]
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200