RPR-260243 [668463-35-2]
HY-16915
Overview
- SupplierMedChem Express
- Product NameRPR-260243 [668463-35-2]
- Delivery Days Customer10
- CAS Number668463-35-2
- CertificationResearch Use Only
- Estimated Purity98.84%
- Molecular FormulaC28H25F3N2O4
- Molecular Weight510.5
- Scientific DescriptionRPR-260243, a potent activator of human ether-a-go-go-related gene (hERG), slows deactivation and attenuates inactivation of hERG1 channels. RPR260243-modified HERG currents are inhibited by Dofetilide (IC50=58 nM). RPR260243 displays no activator-like effects on other voltage-dependent ion channels, including the closely related ERG3 K+ channel.
- SMILESO=C([C@H]1CN(CC#CC2=CC(F)=CC(F)=C2F)CC[C@H]1CCC(C3=CC=NC4=CC=C(OC)C=C34)=O)O
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200